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Initial studies using cancer cells embedded in non-degradable agarose gels showed that compressive stress exerted by the confining matrix on the mammary tumor spheroids suppresses proliferation and survival [117, 118]

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NAC plays a critical role in glutathione production, the body's primary defense against analgesic-related oxidative stress, which can cause liver toxicity and damage

6,21 Hence, this transcriptional addiction offers us an alternate art-of-war that can be adopted to reduce the function of the disease-associated transcription factors