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Conventional models, such as Ishikawa cells, are limited by genomic instability and loss of primary tumor phenotype, underscoring the need for more reliable models [68]

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GPx activity ( Supplementary Figure 3A ) maintained at the baseline level until 1 week after LPS administration and ended the trial with the maximum value, whereas SOD activity ( Supplementary Figure 3B ) remained stable throughout the experiment

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Motivated behavior For the evaluation of carry-over effects, the statistical test for comparing outcome distribution of the two groups at baseline in the second period was not significant ( p = 0.96), indicating no carry over effect