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Mouse tissue measurements showed exposure in metabolically active tissues including adipose tissue, skeletal muscle and liver under the studied conditions

Because the injections are given infrequently with a very small needle (typically a 25-gauge needle is adequate), this is not usually a very unpleasant experience for the cat

Its ability to interact with lipolytic pathways without the confounding growth-promoting effects of full GH makes it particularly useful for dissecting the metabolic arm of GH signalling in laboratory models

This deficiency precludes the formulation of definitive, evidence-based recommendations for their therapeutic use at this time