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413 GLP-1RAs play a neuroprotective role in neurons by facilitating neuronal survival and promoting neuronal growth, thereby preserving the structural and functional integrity of synapses

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4d) and nausea (RR = 3.34, 95% CI 1.74

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Preclinical evidence has suggested that GLP-1R agonists can suppress hepatocellular inflammation and increased oxidative stress indirectly through several cellular pathways that are, in part, independent of weight reduction, since hepatocytes, Kupffer cells, and stellate cells do not express GLP-1Rs [7985]