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GHK suppressed RNA production in 70% of 54 human genes overexpressed in patients with an aggressive metastatic form of colon cancer and was active at a low nontoxic 1 micromolar concentration [62]
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In the future, we will develop small molecule inhibitors or activators for specific transporters such as SLC25A39 and xCT, and use gene editing tools (such as CRISPR/Cas9) to precisely edit related genes to achieve precise regulation of GSH metabolism, providing more targeted means for disease treatment
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