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This is concluded from evidence provided by glucose consumption, 2-NBDG uptake and lactate production measurements as well as ECAR and OCR profiles (Figs 1 and 2)

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Since one of us (S.P.) frequently prescribes GLP-1 receptor agonists for metabolic dysfunction-associated fatty liver disease (MAFLD) patients with obesity, a review of some pearls may be helpful

It is metabolized by the cytochrome P450 family (more specifically CYP2D6) to active metabolites such as endoxifen (4-OH-N-desmethyl-tamoxifen)

Published data on sex-specific sleep effects remain limited