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Some of that testosterone converts to estradiol through aromatase activity

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The effect on stroke is remarkable (and was significant in the trials of both semaglutide and dulaglutide), amounting to an 18% risk reduction, also because the other class of new antidiabetic agents with cardiovascular benefits, the SGLT2-inhibitors, show no a similar effect on stroke (but do have a significant effect on heart failure) [24]

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Eligibility for a semaglutide GLP-1 prescription generally depends on a combination of medical history, current health status, and treatment goals