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These observations prompted us to investigate the expression and function of incretin hormones in monotremes

The Nrf2 gene encodes a transcription factor that is involved in the expression of antioxidant proteins including SOD and glutathione (44), and its high expression is associated with protecting mitochondrial function and combating oxidative stress (45)

"Choline: an essential nutrient for public health." Nutrition Reviews , 67(11), 615-623

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Oxidative stress, along with structural changes such as axonal loss and demyelination from toxic insults like hyperglycemia and alcohol consumption, are also associated factors