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What I see in practice with patients, with friends, and in my own life is that the perimenopause and midlife experience today looks nothing like our mental model

doi: 10.1016/j.molmet.2019.09.010 41 LiYHansotiaTYustaBRisFHalbanPADruckerDJ

In HFrEF, an issue remains that because GLP-1 RAs have been shown to modestly increase heart rate (2-3 beats per minute) owing to their chronotropic effects (see Mechanisms) (Sun et al., 2015), GLP-1 RA treatment in HFrEF may be problematic considering that, in line with the use of beta-blockers to ameliorate HFrEF (11, 12), heart rate elevations may result in a worse outcome (Ibrahim et al., 2019)

These include: GLP-1 weight loss drugs explained Compare Mounjaro, Wegovy, Zepbound How GLP-1s work for weight loss and diabetes Side effects, safety and monitoring Dietary Recommendations Limit sulfur-rich foods (broccoli, cabbage, garlic, eggs)

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