Airborne pollutants like particulate matter (PM), polycyclic aromatic hydrocarbons (PAHs), and heavy metals (such as cadmium and lead) can trigger ROS production when they are inhaled or absorbed into the body
Tie et al, 2009), yet the significance of CBP/p300 (and H3K27ac) to NRF2 activity has not been explored for the broader NRF2 transcriptome
Effective pharmacological therapies include statins for the treatment of dyslipidemia, antiplatelet medicines for the reduction of prothrombotic risk, and insulin sensitizers for the prevention of diabetes
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