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Nesbitt JC, Ajani A, Komaki R, Walsh G, Jr P, JB, Swisher SG , Pisters P, Lynch P, Raijman I, Pazdur R, Delclos M, Martin F, Roth JA

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Seventy percent of study volunteers showed collagen increases compared to untreated controls a response rate significantly higher than that achieved by either comparator compound, both of which are considered first-line clinical options for photoaged skin

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