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(38) administrated a combination of exenatide and nitric oxide synthase inhibitor L-N(G) -monomethyl arginine (L-NMMA) to ten healthy men with a simultaneous automated oscillometric blood pressure recordings, finger photoplethysmography and the analysis of heart rate variability

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Any temperature excursion above 10C for more than 2 hours compromises peptide stability

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As mentioned, several adaptive mutations have been mapped to this protein, and NS4B has been found to encode a GTPase activity that may be related to its membrane-altering ability 68