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As your body gets used to your medication, you should experience less nausea, but in the meantime, there are things you can do to feel better

Based on data from semaglutide and tirzepatide, the improvement in MASH with GLP-1RA appears to be dose-dependent, 50,52 but there are no additional data to explain this

Supported by multidisciplinary care involving surgeons, endocrinologists, dietitians, and behavioral specialists

How to Switch When Starting a New Drug If youre moving from injectable tirzepatide (Zepbound) to the semaglutide pill or orforglipron, the equivalent dose is even less clear because not only are you switching drug forms, youre taking an entirely new drug