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E., Du Toit, L

Compared with the prior art, the invention has the following advantages: (1) The sequence of the coupling reaction is controlled, namely a main peptide chain is coupled with a side chain with a tertiary butyl protection on a carboxyl, then coupled with Boc-His (Trt) -Aib-OH dipeptide, and finally two protecting groups of Boc and t-Bu are simultaneously removed by a one-step method, so that the semaglutide with the purity of more than or equal to 97 percent can be obtained by only 3 steps in the whole process

If this same battery had a 500 milliamp load placed on it, it would take 2 hours to drain down

This can cause an increase in urination

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