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104 Essential oil of Zingiber ottensii plants showed 50% minimum inhibitory activity against human lung cancer cells (A-549) at 43.37 6.69 g/mL, human breast cancer cell lines (MCF-7) at 9.77 1.61 g/mL, human cervix carcinoma cell line (HeLa) at 23.25 7.73 g/mL and myelogenous leukemia cell lines (K562) at 60.49 9.41 g/mL

10.3390/ijms21103443 86 SadeghniaH

The significantly increased 3-hydroxybutyric acid showed that the -oxidation pathway in the liver was activated, that the level of fatty acids was decreased, and that 3-hydroxybutyric acid as a ketone body was produced in large amounts in the liver mitochondria after fatty acid degradation and entered the peripheral blood as alternative fuels to be supplied to other hypoxic tissues, such as the cardiac