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The gut microbiome, shaped by genetic, environmental, and lifestyle factors, plays a crucial role in immune, metabolic, and neural development, with dysbiosis increasingly implicated in the pathogenesis of neurological disorders such as stroke, PD, and AD (Sorboni et al., 2022)
Everything needs to be in balance.[ref][ref] Prostate cancer risk is increased with 4-HOE1(E2) metabolites also.[ref] In general, the estrogen metabolites that start with 2 are good, and the ones that start with 4 or 16 need to be limited or at least eliminated quickly from the body.[ref] Here is a diagram of how these metabolites go together: As you can see, upregulating the CYP1A1 enzyme is going to increase the 2-OHE1 path
Patients on antihypertensive medicines face a risk of additive blood pressure lowering
These antioxidant enzymes include: Superoxide dismutase (SOD): uses copper, zinc, and manganese as cofactors (there is more than one SOD enzyme)
