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German Aerospace Center

Effect of SGLT2 inhibitors on cardiovascular, renal and safety outcomes in patients with type 2 diabetes mellitus and chronic kidney disease: a systematic review and meta-analysis

Safety: Not recommended during pregnancy and may be fatal in large amounts

GI side effects are typically at their peak

Now, there is no doubt in anyone's mind that there have been some adverse events, let's say, on the medication ranging from the more common side effects, the GI side effects everyone is perhaps more familiar with, all the way to issues as extreme as kidney problems, bowel obstruction, unusual tachycardia, IE, heart racing