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NRF2 is a member of the cap n collar (CNC)-bZip transcription factor family that upon recognition of the antioxidant response cis element (ARE) heterodimerizes with small musculoaponeurotic fibrosarcoma (sMAF) proteins to activate transcription (Igarashi et al, 1994

Most of these medications require gradual dose increases over several weeks to months to minimize side effects, including fatigue

[DOI] [PubMed] [Google Scholar] 117.Han C.K., Lee W.F., Hsu C.J., Huang Y.L., Lin C.Y., Tsai C.H., Huang C.C., Fong Y.C., Wu M.H., Liu J.F., et al

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