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Doctors typically prescribe it for 12 weeks at a time to minimize the risk of dependency

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People with a higher level of NNMT have been associated with obesity and type-2 diabetes

Exosomes derived from SiRNA against GRP78 modified bone-marrow-derived mesenchymal stem cells suppress Sorafenib resistance in hepatocellular carcinoma

The primary risks include gastrointestinal side effects (nausea, vomiting, diarrhoea), undesirable weight loss in patients at risk of malnutrition, delayed gastric emptying that may impair levodopa absorption, and rare but serious complications such as pancreatitis and dehydration leading to acute kidney injury