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AND (4) An echocardiogram must be conducted and show valvular lesions of the mitral valve, regurgitation through the mitral valve (MR) on the color Doppler echocardiogram, and have echocardiographic evidence of left atrial and left ventricular dilatation (defined as a left atrial-to-aortic root ratio [LA/Ao] equal to or greater than 1.6 and body weight normalized left ventricular internal diameter in diastole [LVIDDN] equal to or greater than 1.7)

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