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H2O2 is produced in high concentrations by the nicotinamide adenine dinucleotide phosphate (NADPH)-dependent flavoproteins thyroid oxidase DUOX (dual oxidases) 1 and 2 and provides oxidative equivalents for TPO activity [63]

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Non-targeted analyses UHPLC-ESI-QTOFMS analyses Urine samples and medium samples from the in vitro liver models and the enteric bacteria were analyzed using HRMS-based non-targeted methods as described in David et al

Use of KLOW blend is generally considered safe in research but long term use safety data is limited