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NADPH is an abundant antioxidant that acts as an electron donor for several oxidoreductase cycles, such as the GSSG-GSH cycle, biliverdin-bilirubin cycle, and the NQO1 detoxification process (Malhotra et al., 2010

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Modulation of neuroinflammation: curcumin may reduce the release of inflammatory mediators from spinal glia (microglia and astrocytes), reducing neuronal excitability and improving chronic pain [75]

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