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Molecules of nutritional value with antioxidant properties besides GSH, like selenium, zinc and polyphenols, are important in the immune response against SARS-CoV-2 that occurs primary in the lungs (Prez de la Lastra et al., 2021) in critically ill patients with severe COVID-19 acute respiratory distress syndrome (Notz et al., 2021)

Oral Glutathione Absorption Research using radiolabeled glutathione has demonstrated that oral glutathione is extensively broken down by enzymes in the gastrointestinal tract

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if too much medication is taken, these stores are used up, potentially leading to oxidative stress in the liver