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Therefore, targeting the HIF1-c-MYC-PGC1 pathway enhances thermogenesis in beige adipose tissue, thereby providing a potential therapeutic strategy to mitigate obesity and metabolic disorders associated with high-fat diets [142]

doi: 10.1016/s0300-9084(02)01374-3

Phosphate has historically been associated with poor outcomes in patients with APAP hepatotoxicity, with early studies showing an association between low phosphate levels and increased morbidity and mortality