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Studies have shown a correlation between decreased GSH levels and disease

Methionine is then converted into S-adenosylmethionine, which donates methyl groups in reactions catalyzed by methyltransferases, including DNA methylation, producing S-adenosylhomocysteine that is converted back into homocysteine

Applied immediately after ketamine, it exhibited effects on NOS-1 (decreased expression), NOS-2 (increased expression), Plcg1 (decreased expression), Prkcg (increased, and then decreased expression), and Ptgs2 (increased expression), and it had no effect on NOS-3 and Ptk2 [171]

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