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This leads us to hypothesize that the sensitivity of Hcy to changes in is dependent on the strength of the methionine efflux via

Vitamin B12 injections may not be suitable for people who have a history of: allergic reaction or sensitivity to cobalt or vitamin B12 Leber disease kidney disease or impaired kidney function Also, vitamin B12 injections may not be necessary for people without a deficiency

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increasing the expression of mitofusin 1 (MFN1) and mitofusin 2 (MFN2)