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Remarkably, these SP-derived exosomes (denoted as SP EVs) showed similar anti-inflammatory and anti-osteoclastogenic properties when compared with the live SP (Supplementary Figs

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In the absence of appropriate prenylation motifs in HCV proteins, these results suggest that a geranylgeranylated cellular protein participates in HCV replication and could be amenable to pharmacological manipulation

This allows the overlying skin to repair the ageing process and signs of wrinkles, resulting in a smooth young wrinkle-free appearance