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Endoneurial microangiopathy, characterized by capillary abnormalities, occurs early in DPN and correlates with clinical, neurophysiological, and morphological abnormalities

In the mobile phase, solvent A was comprised of water/acetonitrile (95:5, v/v) with 20 mM ammonium acetate (NH 3 AC) and 20 mM ammonia (NH 3 OH) at pH 9