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Kroll, Network models of fluid, hexatic and polymerized membranes

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Glucose deprivation or incubation of the FLS with glycolytic inhibitors has been observed to impair cytokine secretion and decrease the rate of proliferation and migration of the cells

Without uridine, the cell compensates for pyrimidine shortage by over-activating ATP-consuming salvage pathways (UCK2, TK1, dCK), which potentially drives mitochondrial biogenesis to generate more ATP for these phosphorylation reactions 63

doi:10.1056/nejmoa2500969 7.Wharton S, Aronne LJ, Stefanski A, et al