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This is beneficial for minimizing potential side effects and enhancing therapeutic efficacy, as it restricts Dox release primarily to tumor cells, limiting exposure in the circulatory system

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Promotes mitochondrial function and increases insulin sensitivity for people with type 2 diabetes

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The early improvement in glycemic control after RYGB (which would be too early to be due to weight loss) can be explained by the restoration of the first (cephalic) phase of insulin secretion in response to oral glucose (which is absent or severely impaired in type 2 diabetes) [92]