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Nitric oxide production is known to play an important role on mediating angiogenesis 26
Systemic therapy for hepatocellular carcinoma, from the early to the advanced stage: a Japanese perspective
Beyond metabolites, parameters including gas production, pH levels, and fecal inflammatory markers also contribute to defining the state of a healthy microbiota 55,56
BPC 157, L-NAME, L-arginine, NO-relation, in the suited rat ketamine models resembling negative-like symptoms of schizophrenia
Immunological mechanisms The role of immune system in xenobiotics-induced hepatotoxicity is discussed in previous investigations.55 Immune-mediated reactions are suggested to play a role in antithyroid drug-induced hepatotoxicity.56 Although the mechanism(s) underlying this event is not fully elucidated yet 56, but cytokines are thought to play a role in immunemediated liver injury caused by methimazole.56 Cytokines could play an important role in DILI.57,58 Hence, another possible mechanism(s) for antithyroid drugsinduced hepatotoxicity could be immune system-mediated
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