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The stirring continued for another 12 h at room temperature, after which the mixture was transferred into 10 mL of deionized water while being sonicated

Research indicates that gut microbial metabolites, such as SCFAs and -tocopherol, can activate various G protein-coupled receptors (e.g., FFAR2, OLF78, GPBAR1) on the surface of EC cells, thereby promoting the expression of tryptophan hydroxylase 1 (TPH1) and the release of 5-HT (252255)

Since 1978, Immunocal has been awarded 92 patents, and its foundational science has been validated in peer-reviewed medical journals and clinical trials worldwide