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Mitrovi M, Stankovi Popovi V, Erceg S, Perii Mitrovi M, Dobrosavljevi A, Stupar A, Vukovi P, Zlatkovi D, Svorcan P
In SYNCHRONIZE-1, participants lost up to an average of 39.2 lb (17.8 kg) from baseline after 76 weeks of treatment with survodutide, a glucagon/GLP-1 receptor dual agonist 1 The trial met both weight loss primary endpoints and its key secondary endpoint evaluating waist circumference, a predictor of cardiometabolic risk, together demonstrating survodutide's potential to broadly improve metabolic health 1 In addition to these positive results, Boehringer is advancing its broad metabolic health R&D program, exploring multiple pharmaceutical approaches to weight management including oral treatments Ingelheim, Germany
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We also analyzed the oxidation kinetics for roGFP2 WT using the mono- and dithiol variants PfGrx C32S/C88S and PfGrx C88S following pre-treatment with the disulfide bond-inducing redox reagent 3-(dimethylcarbamoylimino)1,1-dimethylurea (Diamide) 76 (Fig