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The average intensity was calculated from the response of the panelists to each sensory characteristic

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However, when stratified by transcriptional subtype, intermediate organoid lines appeared to benefit the most from the addition of ML210 in the context of SHP2/MEK inhibition and basal-like and classical organoid lines in the context of pan-RAS inhibition (Fig

Determination of plasma IL-1 and TNFalpha levels A venous blood sample was withdrawn from the vena cava into EDTA-containing vials in order to determine the plasma level of interleukin-1 beta (IL-1) and tumor necrosis factor alpha (TNFalpha) by ELISA technique (BioSource International, Camarillo, CA, USA)