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The reclassification to Category 2 may serve as a catalyst for pharmaceutical companies and research institutions to invest in the rigorous clinical trials required for formal FDA approval

The clinic answer In a UK clinic, cold-chain storage, stock rotation and expiry checks are routine, so you never have to think about any of this

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Studies in mice, rats, rabbits, and dogs found no severe toxic effects across a wide dose range from 6mcg/kg to 20mg/kg

Furthermore, the fact that only 50% of patients in the intervention group achieved significant pain relief reflects the refractory nature of this condition in many patients