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These data are consistent with evidence that primary cilia present in insulin-producing cells are implicated in regulating glucose metabolism, insulin signaling, and insulin secretion (14, 16, 17)

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We acknowledge several limitations of our study

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Therefore, regular ophthalmologic evaluations are recommended for patients initiating GLP-1 therapy

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Despite the direct effects of SGLT-1 in glucose-induced GLP-1 hormone secretion, inhibition of this transporter can indirectly increase GLP-1 secretion

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