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In a cohort of 74 patients with biopsy-proven NASH, 48-week treatment with rosiglitazone combined with diet and physical activity, compared to diet and exercise alone, was shown to significantly ameliorate NAS, steatosis, and ballooning, but no effect was detected on fibrosis [45]

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So these types of customizations are relatively well established and I think the clinical necessity of compounding and the clinical necessity of personalizing medication is really well established, right

[PowerPoint Presentation] [13] FDA, UPDATED MEETING, supra note 4