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This medication works by mimicking GLP-1 hormones to enhance insulin release, suppress glucagon, slow gastric emptying, and reduce hunger pangs

As such, the observed incidence rate of NAION of 0228 per 1000 person-years for persons with T2D exposed with once-weekly semaglutide may not discourage semaglutide treatment but needs to be acknowledged as a potential risk

Risk of cardiovascular outcomes in patients with type 2 diabetes after addition of SGLT2 inhibitors versus sulfonylureas to baseline GLP-1RA therapy

When GLP-1 is released, it tells the pancreas to release insulin , which helps lower blood glucose

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