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The disconnect between short plasma half-life and prolonged therapeutic effects observed in many studies supports tissue-level mechanisms extending beyond circulating peptide concentrations
Any impact on biological age or telomeres is considered exploratory
Kang DW, Adams JB, Gregory AC, et al
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It is highly expressed in the epithelium of the esophagus, duodenum of the small intestine, and cecum of the large intestine, suggesting its involvement in zinc efflux and absorption into the systemic circulation
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