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The zebrafish model has emerged as a powerful system for deconstructing this complexity (Table 3), owing to its high evolutionary conservation in liver morphology and function, including a well-characterized suite of CYP450 enzymes and a drug metabolism system that parallels human pathways (Goldstone et al., 2010)
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This verifies purity, potency, and ensures the absence of harmful contaminants
This finding is important for researchers planning longer-term protocols and is a detail that many sources overlook