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Preclinical data presented at ADA 2024 showed that HM15275 delivered superior weight loss efficacy compared to semaglutide (Wegovy) and tirzepatide (Zepbound), with relatively less reductions in lean mass

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Moreover, it inhibited the expression of LC3, Beclin1, PINK1, and Parkin, and promoted the expression of Mfn1, Mfn2, and OPA1

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