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These mechanisms not only support glycaemic control and metabolic improvements but also contribute to weight loss by increasing satiety, reducing appetite and food cravings, lowering the preference for high-fat and energy-dense foods, and improving overall eating behaviour (Fig
GLP-1s reduce cravings and food noise , especially for sweet, high-calorie items
Another class of medications initially developed for the treatment of high blood glucose in patients with type 2 diabetes, sodium-glucose cotransporter 2 inhibitors (SGLT2i), has also been demonstrated to reduce cardiovascular risk, with corresponding FDA product label changes and professional society recommendations endorsing their use
Dosing starts low at 2.5mg weekly and increases every 4 weeks based on your response and tolerability