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With major vascular occlusions, there was, at the periphery, the leading role of the rapid heart disturbances, and thereby, heart, lung, liver, kidney and gastrointestinal lesions, inferior and superior vena caval congestion, azygos vein failure, portal and caval hypertension and aortal hypotension occur [14,15,16,17,18,19,20]

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Glutathione depletion enforces the mitochondrial permeability transition and causes cell death in Bcl-2 overexpressing HL60 cells