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Because native IGF-1 suppresses GH release when it rises, the endogenous axis is self-limiting the system resists runaway signaling

However, this apparent heterogeneity of health effects across UPF subgroups is contentious and may reflect biases and flawed comparisons with the rest of the diet rather than with non-ultra-processed counterparts (104)

SK: Methodology, Writing review & editing, Data curation

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