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Bruising: Occasionally unavoidable, especially if you hit a small blood vessel

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Participants began at a 2 mg starting dose and stepped up roughly every four weeks toward their assigned target

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The main enzyme involved, dipeptidyl peptidase-4 (DPP-4) also known as CD26, cleaves off the two N-terminal residues resulting in GLP-1 (9-36 amide) which is inactive or acts as an inhibitor at the GLP-1 receptor (23)

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