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Carnosic acid inhibits reactive oxygen species-dependent neutrophil extracellular trap formation and ameliorates acute respiratory distress syndrome

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Figure 3 2.1.2.1 TLR9/MyD88 pathway TLR9 senses mtDNA and drives inflammatory responses in surgical settings (34), TLR9 knockout mice are protected from some forms of sterile organ injury

To answer that question, it is important to first understand how we got here