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MOTS-c, by contrast, is not derived from hGH at all its research relevance comes from mitochondrial retrograde signaling, a communication pathway between mitochondria and the rest of the cell that governs how energy production adapts under metabolic stress

Primary Research Areas NNMT enzymology and pharmacology the lead first-in-class selective small-molecule NNMT inhibitor used to validate the entire target class [1,2]