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In this group, circulating TMAO was associated with reduced values of estimated glomerular filtration rate (eGFR, Spearman rho = 0.124, pFDR = 0.06) and higher fasting concentrations of uric acid (rho = 0.114, pFDR = 0.09) after adjustment for age, sex, country of recruitment (demographics thereafter) and body mass index (BMI) (Supplementary Fig

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