Accumulation of senescent cells in tissues has been associated with age-related functional decline, chronic inflammation, and impaired tissue regeneration
Therefore, the development of resistance to radiotherapy is one of the toughest challenges in disease management
doi: 10.3389/fphar.2021.667753 Received 14 February 2021 Accepted 30 June 2021 Published 14 July 2021 Volume 12 - 2021 Edited by Francesca Viazzi, Ospedale San Martino (IRCCS), Italy Reviewed by Elisa Russo, University of Genoa, Italy Daniela Verzola, University of Genoa, Italy Updates Copyright 2021 Sun, Wu, Bian, Yang, Wang, Meng and Jin
doi: 10.3390/cells12182304 168
Subjects and methods Study design We conducted a two-sample MR study based on well-established large cohorts and consortia (Additional file 1: Table S1 and Additional file 2: Fig