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Laboratory investigations have revealed FOXO4-DRI's exceptional selectivity for senescent cells, with research demonstrating that more than 80% of senescent cells undergo apoptosis while healthy cells remain unaffected

The decision attracted coverage from CNN, NPR, PBS NewsHour, ABC News, The Associated Press, The Washington Post, and other national outlets

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In particular, several previously highlighted genes, including ANXA1 and RAN , showed directionally consistent L-serineassociated trends along the trajectories in this sensitivity analysis (Supplementary Fig

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